Human Skin CD141⁺ Dendritic Cells Regulate Cutaneous Immunity via the Neuropeptide Urocortin-2

The authors demonstrated CD141+ dermal dendritic cells (DCs) and CD141hiVitD3 monocyte-derived DCs shared key immunological features including cell surface markers, reduced T cell stimulation, IL-10 production, and a common transcriptomic signature.