A Next-Generation Intranasal Trivalent MMS Vaccine Induces Durable and Broad Protection Against SARS-CoV-2 Variants of Concern

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By expressing the six-proline-stabilized prefusion spikes from three diverse SARS-CoV-2 strains in the MeV, MuV-JL1, and MuV-JL2 vaccine strains from MMR, researchers generated a MMS trivalent vaccine candidate.
[Proceedings Of The National Academy Of Sciences Of The United States Of America]
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