Inhibition of IL-17 Ameliorates Keratinocyte-Borne Cytokine Responses in an In Vitro Model for House-Dust-Mite Triggered Atopic Dermatitis

Peripheral blood mononuclear cells derived from respectively sensitized atopic dermatitis patients were stimulated with house dust mite extract and cell culture supernatants were applied subsequently in absence or presence of secukinumab to primary human keratinocytes.