Cancer Stem Cell-Derived CHI3L1 Activates the MAF/CTLA4 Signaling Pathway to Promote Immune Escape in Triple-Negative Breast Cancer

Researchers utilized single-cell transcriptome sequencing to uncover the molecular mechanisms by which the CHI3L1/MAF/CTLA4 signaling pathway may mediate immune evasion in triple-negative breast cancer through the interaction between tumor stem cells and immune cells.