CD146 Promotes Malignant Progression of Breast Phyllodes Tumor through Suppressing DCBLD2 Degradation and Activating the AKT Pathway

The efficacy of anti-CD146 monoclonal antibody AA98 against malignant phyllodes tumors (PTs) was corroborated by a malignant PT organoid model and a PT patient-derived xenograft model.