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Scientists tested the hypothesis that extracellular superoxide dismutase (ecSOD) modified TNFα signaling in vascular smooth muscle cells. Knockdown of ecSOD suppressed downstream TNFα signals.
[Free Radical Biology and Medicine]
Extracellular SOD Modulates Canonical TNFα Signaling and α5β1 Integrin Transactivation in Vascular Smooth Muscle Cells
