Identification and Characterization of CD8⁺CD27⁺CXCR3⁻ T Cell Dysregulation and Progression-Associated Biomarkers in Systemic Lupus Erythematosus

The comprehensive immune cell dysregulation in total 263 clinical peripheral blood samples composed of active systemic lupus erythematosus (SLE), remission SLE, and healthy controls was investigated via mass cytometry, flow cytometry, and single-cell RNA sequencing.