Ebf3⁺ Niche-Derived CXCL12 Is Required for the Localization and Maintenance of Hematopoietic Stem Cells

Researchers showed that in mice whose CXC chemokine ligand 12 (CXCL12) was deleted from half HSC niche cells, HSCs migrated from CXCL12-deficient niches to CXCL12-intact niches.