Salicylate Induces AMPK and Inhibits c-MYC to Activate a NRF2/ARE/miR-34a/b/b Cascade Resulting in Suppression of Colorectal Cancer Metastasis

Researchers found that salicylate induces the expression of the miR-34a and miR-34b/c genes, which encoded tumor suppressive microRNAs, in a p53-independent manner.