Interference of MDM2 Attenuates Vascular Endothelial Dysfunction in Hypertension Partly Through Blocking Notch1/NLRP3 Inflammasome Pathway

Researchers found that the knockdown of MDM2 can attenuate vascular endothelial dysfunction in hypertension, which may be achieved by inhibiting the activation of Notch1 and NLRP3 inflammasome.