Atovaquone Inhibits Colorectal Cancer Metastasis by Regulating PDGFRβ/NF-κB Signaling Pathway

Investigators showed that atovaquone could inhibit colorectal cancer metastasis and invasion in vivo and in vitro, inhibit the expression of E-cadherin protein, and promote the protein expression of N-cadherin, vimentin, ZEB1, Snail, and Slug.