Mutant p53 and ELK1 Co-Drive FRA-1 Expression to Induce Metastasis in Breast Cancer

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By comparing the gene expression profiles of mutant p53 (mutp53) and mutp53 silenced cohorts, investigators found that FOS-related antigen-1 (FRA-1) was a potential effector of mutp53-mediated metastasis.
[FEBS Letters]
Abstract