EGFR Promotes ALKBH5 Nuclear Retention to Attenuate N6-Methyladenosine and Protect against Ferroptosis in Glioblastoma

Investigators showed that epidermal growth factor receptor (EGFR) signaling repressed N6-methyladenosine (m6A) levels in glioblastoma stem cells, whereas genetic or pharmacologic EGFR targeting elevated m6A levels.