The miR-221/222 Cluster Regulates Hematopoietic Stem Cell Quiescence and Multipotency by Suppressing Both Fos/AP-1/IEG Pathway Activation and Stress-Like Differentiation to Granulocytes

By
Laurisa Dohm
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0
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The authors found that the miR-221/222 cluster, which was expressed in HSC and in multipotent progenitors differentiating from them, perturbed steady-state hematopoiesis in ways comparable to stress.
[PLOS Biology]
Abstract