YTHDF1 Enhances Stemness and Chemoresistance in Triple-Negative Breast Cancer Cells by Upregulating SIAH2

Knockdown of YTHDF1 and SIAH2, or overexpression of seven in absentia homology 2 (SIAH2) in vitro and in vivo, was conducted to evaluate the impact of changes in YTHDF1 and SIAH2 expression on TNBC cell proliferation, apoptosis, stemness, drug resistance, and Hippo pathway gene expression.