SOX8 Promotes Tumor Growth and Metastasis through FZD6-Dependent Wnt/β-Catenin Signaling in Colorectal Carcinoma

Data showed that SOX8 expression was upregulated in colorectal carcinoma (CRC) cell lines and tumor tissues. Stable knockdown of SOX8 in CRC cell lines dramatically reduced cell proliferation, migration, and invasion.