Nicotinamide Mononucleotide Impacts HIV-1 Infection by Modulating Immune Activation in T Lymphocytes and Humanized Mice

Investigators examined HIV-1 integrated DNA or transcribed RNA, intracellular p24 protein, and T cell activation markers in CD4+ T cells including in vitro HIV-1-infected cells, reactivated patient-derived cells, and in HIV-1-infected humanized mice, under NMN treatment.