S-Adenosylmethionine Attenuates Angiotensin II-Induced Aortic Dissection Formation by Inhibiting Vascular Smooth Muscle Cell Phenotypic Switch and Autophagy

The authors constructed an animal model of Alzheimer’s disease (AD) using subcutaneous minipump continuous infusion of AngII-induced ApoE-/-mice and a cytopathic model using AngII-induced primary vascular smooth muscle cells to investigate the possible role of S-adenosylmethionine in AD.