Single-Cell Transcriptome Sequencing Reveals Spatial Distribution of IL34⁺ Cancer-Associated Fibroblasts in Hepatocellular Carcinoma Tumor Microenvironment

Scientists acquired scRNA-seq datasets about HCC, which enabled them to identify distinct cell subpopulations within HCC tissues. They conducted a differential analysis to pinpoint DEGs associated with normal fibroblasts (NFs) and cancer-associated fibroblasts (CAFs).