Thrombin Priming Promotes the Neuroprotective Effects of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells via the HGF/Akt/STAT3 Signaling Pathway

Researchers characterized thrombin-primed Wharton’s Jelly (Th.WJ)-derived-MSCs in terms of stem cell markers, differentiation, cell proliferation, and paracrine factors by comparing naïve and Th.WJ-MSCs. They demonstrated that compared with naïve MSCs, Th.MSCs significantly enhanced the neuroprotective effects in vitro/.