Lymphatic Endothelial-Like Cells Promote Glioblastoma Stem Cell Growth through Cytokine-Driven Cholesterol Metabolism

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Investigators showed that lymphatic endothelial-like cells, while previously unrecognized in brain parenchyma, were present in glioblastomas and promoted growth of CCR7-positive glioblastoma stem cells through CCL21 secretion.
[Nature Cancer]
Abstract