In Vivo Measurement of RBC Survival in Patients with Sickle Cell Disease before or after Hematopoietic Stem Cell Transplantation

Researchers utilized biotin-labeling of red blood cells (RBCs) to determine the lifespan of RBCs in patients with sickle cell disease compared to patients who have successfully undergone curative hematopoietic stem cell transplantation, participants with sickle cell trait, and healthy donors.