Ryanodine Receptor Dysfunction Causes Senescence and Fibrosis in Duchenne Dilated Cardiomyopathy

Researchers used hiPSC-cardiomyocytes from Duchenne muscular dystrophy (DMD) patients selected by Speckle-tracking echocardiography and canine DMD cardiac biopsies to assess key early-stage Duchenne dilated cardiomyopathy features.