CPX-351 Exploits the Gut Microbiota to Promote Mucosal Barrier Function, Colonization Resistance and Immune Homeostasis

Investigators evaluated the impact of CPX-351 and “7+3” combination on mucosal barrier function, gut microbial composition and function and antifungal colonization resistance in preclinical models of intestinal damage in vitro and in vivo and fecal microbiota transplantation.