Tricarboxylic Acid Cycle Metabolite-Coordinated Biohydrogels Augment Cranial Bone Regeneration Through Neutrophil-Stimulated Mesenchymal Stem Cell Recruitment and Histone Acetylation-Mediated Osteogenesis

The immune microenvironment- and MSC fate-regulated citrate-coordinated CGG hydrogels represented a highly efficient and facile approach toward skull bone tissue regeneration with great potential for bench-to-bedside translation.