Fructose Potentiates Bone Loss and Marrow Adipose Tissue Accumulation by Inhibiting Adenosine 5′-Monophosphate-Activated Protein Kinase in Mesenchymal Stem Cells

Investigators identified fructose deteriorated bone mineral density while promoting the abundance of bone marrow adipose tissue. Fructose remarkably promoted the bone marrow MSCs adipogenic commitment at the expense of osteogenic commitment.