Pro-BDNF, but Not Mature BDNF, Is Expressed in Human Skeletal Muscle: Implications for Exercise-Induced Neuroplasticity

Investigators quantified the expression of pro-BDNF and mBDNF in human skeletal muscle and plasma at rest, after acute exercise, and after fasting. Pro-BDNF and mBDNF were analyzed with immunoblotting, ELISA, immunohistochemistry, and qPCR.