GTS-21 Attenuates ACE/ACE2 Ratio and Glycocalyx Shedding in Lipopolysaccharide-Induced Acute Lung Injury by Targeting Macrophage Polarization Derived ADAM-17

Researchers developed mouse models of acute lung injury and alveolar epithelial type II cells injury following treatment with lipopolysaccharides and different polarized macrophage supernatants, respectively.