FSTL3 Promotes Tumor Immune Evasion and Attenuates Response to Anti-PD1 Therapy by Stabilizing c-Myc in Colorectal Cancer

Researchers revealed that follistatin-like 3 (FSTL3) were overexpressed in malignant cells in the colorectal cancer microenvironment, notably, the expression level of FSTL3 was related to tumor immune evasion and the clinical efficacy of anti-PD1 therapy.