Tumor Circadian Clock Strength Influences Metastatic Potential and Predicts Patient Prognosis in Luminal a Breast Cancer

Scientists reconstructed rhythms informatically, integrating locally collected, time-stamped biopsies with public datasets. For noncancerous breast tissue, inflammatory, epithelial–mesenchymal transition, and estrogen responsiveness pathways show circadian modulation.
[Proceedings Of The National Academy Of Sciences Of The United States Of America]
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