Helicobacter pylori CagA Protein Induces Gastric Cancer Stem Cell-Like Properties through the Akt/FOXO3a Axis

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Researchers revealed that CagA-positive gastric cancer cells infected with H. pylori exhibited CSC-like properties, such as heightened expression of CD44, a specific surface marker for CSCs, and increased ability to form tumor spheroids.
[Journal of Cellular Biochemistry]
Abstract