Effect of Chitin-Architected Spatiotemporal Three-Dimensional Culture Microenvironments on Human Umbilical Cord-Derived Mesenchymal Stem Cells

Scientists used chitin-based nanoscaffolds to establish a novel MSC three-dimensional (3D) culture. We compared 2D and 3D cultured human umbilical cord-MSCs, including differentiation assays, cell markers, proliferation, and angiogenesis.