Clonal Hematopoiesis of Indeterminate Potential with Loss of Tet2 Enhances Risk for Atrial Fibrillation through Nlrp3 Inflammasome Activation

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Clonal hematopoiesis of indeterminate potential (CHIP) prevalence was determined in the UK Biobank, and incident atrial fibrillation analysis was stratified by CHIP status and clone size using Cox proportional hazard models.
[Circulation]
Abstract