MSC-Derived Small Extracellular Vesicles Exert Cardioprotective Effect through Reducing VLCFAs and Apoptosis in Human Cardiac Organoid IRI Model

Human embryonic stem cell-derived chambered cardiac organoid was used as a model system to study the effects of mesenchymal stem cell (MSC)-derived small extracellular vesicles on myocardial ischemia-reperfusion injury (IRI).