Durable Cross-Protective Neutralizing Antibody Responses Elicited by Lipid Nanoparticle-Formulated SARS-CoV-2 mRNA Vaccines

Researchers assessed the efficacy of lipid nanoparticles-encapsulated mRNA booster vaccines encoding the spike protein of SARS-CoV-2 for variants of concern and using a predecessor strain spike protein to elicit durable cross-protective neutralizing antibody responses.