Core-Shell Nanofibers Containing L-arginine Stimulates Angiogenesis and Full Thickness Dermal Wound Repair

Coaxial electrospinning was employed to fabricate core–shell nanofiber-based wound dressing, with core composed of polyacrylamide and shell comprising 0.5 % solution of L-Arginine in aloe vera and keratin. Aloe vera and keratin were added as natural polymers to promote angiogenesis, reduce inflammation, and provide antibacterial activity.