Devastating the Supply Wagons: Multifaceted Liposomes Capable of Exhausting Tumor to Death via Triple Energy Depletion

A novel treatment paradigm of starving-like therapy—triple energy-depleting therapy—is illustrated by glucose oxidase/dc-IR825/sorafenib liposomes, and such a triple energy-depleting therapy exhibits a more effective tumor-killing effect than conventional starvation therapy that only cuts off one of the energy supplies.