Tumor-Derived Exosomal ADAM17 Promotes Pre-Metastatic Niche Formation by Enhancing Vascular Permeability in Colorectal Cancer

Investigators discovered that exosome-derived disintegrin and metalloproteinase 17 (ADAM17) derived from the circulating exosomes of patients with colorectal cancer could serve as a blood-based biomarker for predicting metastasis.