NewslettersExtracellular Matrix NewsPolyGR and polyPR Knock-In Mice Reveal a Conserved Neuroprotective Extracellular Matrix Signature in C9orf72 ALS/FTD NeuronsBy Jamie Kang - February 29, 2024032Investigators generated C9orf72 dipeptide repeat knock-in mouse models characterized by the expression of 400 codon-optimized polyGR or polyPR repeats, and heterozygous C9orf72 reduction.[Nature Neuroscience]Full Article