Flvcr1a Deficiency Promotes Heme-Based Energy Metabolism Dysfunction in Skeletal Muscle

Scientists generated a skeletal-muscle-specific feline leukemia virus subgroup C receptor 1a (FLVCR1a) knockout mouse model and showed that, by sustaining heme synthesis, FLVCR1a contributed to determine the energy phenotype in skeletal muscle cells and to modulate satellite cell differentiation and muscle regeneration.