Daturataturin a Ameliorates Psoriasis by Regulating PPAR Pathway

Researchers elucidated the effect of daturataturin A on psoriasis and its potential mechanism. They established a daturataturin A psoriasis-like keratinocytes model by stimulating HaCaT cells with M5 cocktail cytokines including Interleukin (IL)-17A, IL-22, oncostatin M, IL-1α, and tumor necrosis factor-α (TNF-α), followed by intervention with DTA.