Cell Morphology Best Predicts Tumorigenicity and Metastasis In Vivo across Multiple TNBC Cell Lines of Different Metastatic Potential

Investigators sought to classify each breast cancer cell line as poorly or highly metastatic by characterizing tumor growth and metastasis in a murine model of six commonly used human triple-negative breast cancer xenografts, as well as determine which in vitro assays commonly used to study cell motility best predict in vivo metastasis.