Highly Bioadaptable Hybrid Conduits with Spatially Bidirectional Structure for Precision Nerve Fiber Regeneration via Gene Therapy

Researchers presented a scaffold that facilitated the localized administration of the transforming growth factor β gene in the proximal region to accelerate nerve regeneration, while simultaneously delivering nicotinamide mononucleotide adenylyltransferase 2 to the distal region to mitigate Wallerian degeneration.