Mutant Huntingtin Protein Induces MLH1 Degradation, DNA Hyperexcision, and cGAS–STING-Dependent Apoptosis

By
Noshin Noorjahan
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0
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Investigators show that huntingtin (HTT) interacted with both exonuclease 1 (Exo1) and MutLα, a negative regulator of Exo1.
[Proceedings Of The National Academy Of Sciences Of The United States Of America]
Abstract