Noggin Promotes Osteogenesis in Human Adipose-Derived Mesenchymal Stem Cells via FGFR2/Src/Akt and ERK Signaling Pathway

The authors showed that in osteogenic cultures of adipose-derived stem cells, Noggin activated fibroblast growth factor receptors (FGFRs), Src/Akt and ERK kinases, and it stabilized TAZ proteins in the presence of dexamethasone.