An Anti-Infection and Biodegradable TFRD-Loaded Porous Scaffold Promotes Bone Regeneration in Segmental Bone Defects -Experimental Studies

Inspired by the local use of total flavonoids of Rhizoma Drynariae in the treatment of fracture, a novel 3D-printed HA/CMCS/PDA/TFRD scaffold with anti-infection, biodegradable and induced angiogenesis was designed, and to explore its preclinical value in segmental bone defect of tibia.