Identification and Removal of Unexpected Proliferative Off-Target Cells Emerging after iPSC-Derived Pancreatic Islet Cell Implantation

Investigators showed that the implantation of seven-stage induced PSC-derived pancreatic islet cells led to the emergence of unexpected off-target cells with proliferative capacity via in vivo maturation.
[Proceedings Of The National Academy Of Sciences Of The United States Of America]
Full Article