Cellular Trojan Horse Initiates Bimetallic Fe-Cu MOF-Mediated Synergistic Cuproptosis and Ferroptosis Against Malignancies

Investigators engineered a Cellular Trojan Horse, named MetaCell, which used live neutrophils to stably internalize thermosensitive liposomal bimetallic Fe-Cu MOFs. MetaCell could instigate cuproptosis and ferroptosis, thereby enhancing treatment efficacy.