Dual-Targeted Novel Temozolomide Nanocapsules Encapsulating siPKM2 Inhibit Aerobic Glycolysis to Sensitize Glioblastoma to Chemotherapy

To effectively inhibit aerobic glycolysis, increase drug delivery efficiency, and improve drug sensitivity, researchers successfully designed and prepared a novel TMZ nanocapsule for the combined delivery of siPKM2 and TMZ.