Comparative Performance of scFv-Based Anti-BCMA CAR Formats for Improved T Cell Therapy in Multiple Myeloma

CD8TM.41BBIC-based anti-BCMA CAR vectors with either a long linker or a short linker between the light and heavy scFv chain, CD28TM.41BBIC-based and CD28TM.CD28IC-based anti-BCMA CAR vector systems were used in primary human T cells.